Sample and Predict harmful algae blooms.
In many aquatic ecosystems world-wide, including drinking water supplies, cyanobacteria and dinoflagellates can proliferate into the so-called harmful algal blooms (HAB). Members of these microbial phyla can produce an unparalleled array of bioactive secondary metabolites; some of which are potent toxins. The past ten years has witnessed major advances in our understanding of the genetic basis for toxin production by a number of groups of these microorganisms.
Genomic information related to toxin synthesis has also indicated their environmental and cellular regulators, as well as associated transport mechanisms. The information gained from the discovery of these toxin biosynthetic pathways has also enabled the genetic screening of various environments for drinking water and seafood quality management.
Diagnostic Technology is developing and validating a molecular based test for the detection of cyanotoxin production in fresh, brackish and marine water environments, that pose a direct threat to public health. The CyanoDTec is a simple molecular assay for the simultaneous detection of hepatotoxins such as microcystin, nodularin and cylindrospermopsin and neurotoxins such as saxitoxin.